Kejadian Mortalitas Wanita dengan Kanker Payudara Berdasarkan Indeks Massa Tubuh (BMI): Tinjauan Naratif

DOI: 10.29241/jmk.v10i1.1879

Author

Anita Dahliana(1*), Agung Anjar Sukmantoro(2), Rivan Virlando Suryadinata(3), Titin Wahyuni(4), Dwi Martha Nur Aditya(5)

(1) Universitas Surabaya
(2) Universitas Surabaya
(3) Universitas Surabaya
(4) STIKES Yayasan RS Dr. Soetomo
(5) Universitas Surabaya
(1*) Corresponding Author

Full Text

Full Text: View / Download PDF

Article Metrics

Abstract View : 331 times; PDF Download : 250 times

Abstract

Breast cancer is the most common cancer found in women of all types of cancer in the world. The relationship between body mass index and the death rate from breast cancer in women has drawn attention recently. This study sought to ascertain the relevance of the variation in death rates between women with breast cancer who had a normal body mass index (BMI) and those who had a BMI of ≥25. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) references were used to guide the systematic review process in this investigation. The Newcastle-Ottawa Scale for cohort design studies and the Robins-I test for single-arm experimental design studies were used to assess the quality of the articles. The data source consisted of 142 Pubmed publications published between 2016 and 2023. The analysis's findings revealed differences between the five publications that discussed the connection between obesity and breast cancer.  The development of breast cancer is linked to an increase in leptin and estrogen, which is consistent with an increase in fat. It is concluded that individuals with a body mass index (BMI) of ≥ 25 had a poorer chance of surviving breast cancer than patients with a normal BMI.

Keywords

Breast Cancer, Body Mass Index, Obesity

References

Ahmadi, S.-F., Streja, E., Zahmatkesh, G., Streja, D., Kashyap, M., Moradi, H., … Kalantar-Zadeh, K. (2015). Reverse Epidemiology of Traditional Cardiovascular Risk Factors in the Geriatric Population. Journal of the American Medical Directors Association, 16(11), 933–939. https://doi.org/10.1016/j.jamda.2015.07.014

Arnold, M., Charvat, H., Freisling, H., Noh, H., Adami, H.-O., Soerjomataram, I., & Weiderpass, E. (2019). Adult Overweight and Survival from Breast and Colorectal Cancer in Swedish Women. Cancer Epidemiology, Biomarkers & Prevention, 28(9), 1518–1524. https://doi.org/10.1158/1055-9965.EPI-19-0075

Cortesi, L., Sebastiani, F., Iannone, A., Marcheselli, L., Venturelli, M., Piombino, C., … Federico, M. (2020). Lifestyle Intervention on Body Weight and Physical Activity in Patients with Breast Cancer Can Reduce the Risk of Death in Obese Women: The EMILI Study. Cancers, 12(7), 1709. https://doi.org/10.3390/cancers12071709

DeSantis, C. E., Ma, J., Gaudet, M. M., Newman, L. A., Miller, K. D., Goding Sauer, A., … Siegel, R. L. (2019). Breast cancer statistics, 2019. CA: A Cancer Journal for Clinicians, 69(6), 438–451. https://doi.org/10.3322/caac.21583

Elwood, J. M., Tin Tin, S., Kuper-Hommel, M., Lawrenson, R., & Campbell, I. (2018). Obesity and breast cancer outcomes in chemotherapy patients in New Zealand – a population-based cohort study. BMC Cancer, 18(1), 76. https://doi.org/10.1186/s12885-017-3971-4

Hua, H., Zhang, H., Kong, Q., & Jiang, Y. (2018). Mechanisms for estrogen receptor expression in human cancer. Experimental Hematology & Oncology, 7(1), 24. https://doi.org/10.1186/s40164-018-0116-7

Kemenkes RI. (2019). Hari Kanker Sedunia.

Liu, Y. L., Saraf, A., Catanese, B., Lee, S. M., Zhang, Y., Connolly, E. P., & Kalinsky, K. (2018). Obesity and survival in the neoadjuvant breast cancer setting: role of tumor subtype in an ethnically diverse population. Breast Cancer Research and Treatment, 167(1), 277–288. https://doi.org/10.1007/s10549-017-4507-y

Mair, K. M., Gaw, R., & MacLean, M. R. (2020). Obesity, estrogens and adipose tissue dysfunction – implications for pulmonary arterial hypertension. Pulmonary Circulation, 10(3), 1–21. https://doi.org/10.1177/2045894020952023

Moore, A. H., Trentham-Dietz, A., Burns, M., Gangnon, R. E., Greenberg, C. C., Vanness, D. J., … Fleming, S. T. (2018). Obesity and mortality after locoregional breast cancer diagnosis. Breast Cancer Research and Treatment, 172(3), 647–657. https://doi.org/10.1007/s10549-018-4932-6

Neil-Sztramko, S. E., Boyle, T., Milosevic, E., Nugent, S. F., Gotay, C. C., & Campbell, K. L. (2017). Does obesity modify the relationship between physical activity and breast cancer risk? Breast Cancer Research and Treatment, 166(2), 367–381. https://doi.org/10.1007/s10549-017-4449-4

Pan, K., Chlebowski, R. T., Mortimer, J. E., Gunther, M. J., Rohan, T., Vitolins, M. Z., … Nelson, R. A. (2020). Insulin resistance and breast cancer incidence and mortality in postmenopausal women in the Women’s Health Initiative. Cancer, 126(16), 3638–3647. https://doi.org/10.1002/cncr.33002

Ray, A. (2012). Adipokine leptin in obesity-related pathology of breast cancer. Journal of Biosciences, 37(2), 289–294. https://doi.org/10.1007/s12038-012-9191-9

Sánchez-Jiménez, F., Pérez-Pérez, A., de la Cruz-Merino, L., & Sánchez-Margalet, V. (2019). Obesity and Breast Cancer: Role of Leptin. Frontiers in Oncology, 9. https://doi.org/10.3389/fonc.2019.00596

Weir, C. B., & Jan, A. (2023). BMI Classification Percentile And Cut Off Points. In StatPearls. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/11234459

WHO. (2018). Cancer. Retrieved from https://www.who.int/news-room/fact-sheets/detail/cancer

Refbacks

  • There are currently no refbacks.




Copyright (c) 2024 Anita Dahliana, Agung Anjar Sukmantoro, Rivan Virlando Suryadinata, Titin Wahyuni, Dwi Martha Nur Aditya

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.